DFF45 (Cleaved-Thr225) rabbit pAb
CAT:
855-ES19986-01
Size:
50 μL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DFF45 (Cleaved-Thr225) rabbit pAb
- Description: Function: Inhibitor of the caspase-activated DNase (DFF40). PTM: Caspase-3 cleaves DFF45 at 2 sites to generate an active factor. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Contains 1 CIDE-N domain. subunit: Heterodimer of DFFA and DFFB.
- Synonyms: DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit;DFF-45;Inhibitor of CAD;ICAD)
- Gene ID: 1676
- UniProt: O00273
- Cellular Locus: Cytoplasm.
- Host: Rabbit
- Species Reactivity: Human, Rat, Mouse,
- Immunogen: Synthesized peptide derived from human DFF45 (Cleaved-Thr225)
- Clonality: Polyclonal
- Validated Applications: WB, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:1000-2000 ELISA 1:5000-20000
- Molecular Weight: 12 36kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.