Anti-Hu CD184 PE-Cy1535

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Dry Ice Shipment: No

Alternative Products

Cat	Name
MBS1801909-02	Anti-Hu CD184 PE
MBS1801909-01	Anti-Hu CD184 PE
MBS1802222-01	Anti-Hu CD184 PE-Cy7
MBS1802222-02	Anti-Hu CD184 PE-Cy7
MBS1802232-02	Anti-Hu CD184 PE-Cy5
MBS1802232-01	Anti-Hu CD184 PE-Cy5
MBS1801854-01	Anti-Hu CD184 APC
MBS1801854-02	Anti-Hu CD184 APC
MBS1801767-01	Anti-Hu CD184 Purified
MBS1801767-02	Anti-Hu CD184 Purified

CAT:

270-T8-146-T100

Size:

100 Tests

Price:

Ask

For price, please contact [email protected].

Anti-Hu CD184 PE-Cy1535

Background: CD184, also known as CXCR4 or fusin, is a receptor for the C-X-C chemokine SDF-1. It is expressed mainly in hematopoietic cells, vascular endothelium, and neural tissue. CD184 is a G-protein coupled receptor containing extracellular N-terminal, seven transmembrane domains and intracellular C-terminal domain. It transduces signal by increasing the intracellular calcium level. CD184 plays an essential role in vascularization of the gastrointestinal tract, and is involved in cerebellar development and in hematopoiesis. It is also a coreceptor (with CD4) for HIV-1 X4 virus and a primary receptor for some HIV-2 isolates.
Specifications: The mouse monoclonal antibody 12G5 recognizes an extracellular epitope of CD184, a 45 kDa G-protein-linked CXC chemokine receptor widely expressed on blood and tissue cells.
Certification: RUO
Host: Mouse
Species Reactivity: Human, Non-human primates
Immunogen: CP-MAC-infected Sup-T1 cells
Target Antigen: CD184
Isotype: IgG2a κ
Clone: 12G5
Applications: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 mL) is sufficient for 100 tests.
Validated Applications: FC
Format: PE-Cy1535
Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations: *Koopman G, Mortier D, Hofman S, Koutsoukos M, Bogers WM, Wahren B, Voss G, Heeney JL: Acute-phase CD4+ T-cell proliferation and CD152 upregulation predict set-point virus replication in vaccinated simian-human immunodeficiency virus strain 89.6p-infected macaques. J Gen Virol. 2009 Apr90(Pt 4):915-26., URL: http://www.ncbi.nlm.nih.gov/pubmed/19223489 ,*Campioni D, Zauli G, Gambetti S, Campo G, Cuneo A, Ferrari R, Secchiero P: In vitro characterization of circulating endothelial progenitor cells isolated from patients with acute coronary syndrome. PLoS One. 20138(2):e56377., URL: http://www.ncbi.nlm.nih.gov/pubmed/23409178 ,*Uy GL, Rettig MP, Motabi IH, McFarland K, Trinkaus KM, Hladnik LM, Kulkarni S, Abboud CN, Cashen AF, Stockerl-Goldstein KE, Vij R, Westervelt P, DiPersio JF: A phase 1/2 study of chemosensitization with the CXCR4 antagonist plerixafor in relapsed or refractory acute myeloid leukemia. Blood. 2012 Apr 26119(17):3917-24., URL: https://pubmed.ncbi.nlm.nih.gov/22308295/,*Grundler R, Brault L, Gasser C, Bullock AN, Dechow T, Woetzel S, Pogacic V, Villa A, Ehret S, Berridge G, Spoo A, Dierks C, Biondi A, Knapp S, Duyster J, Schwaller J: Dissection of PIM serine/threonine kinases in FLT3-ITD-induced leukemogenesis reveals PIM1 as regulator of CXCL12-CXCR4-mediated homing and migration. J Exp Med. 2009 Aug 31206(9):1957-70., URL: https://pubmed.ncbi.nlm.nih.gov/19687226/,
Storage Conditions: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Complementary Product Range

Our range of products, including Anti-Hu CD184 PE-Cy1535, falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

Each item in our collection, is tested for precision and quality, ensuring dependable solutions for your research. As we continue to incorporate the latest advancements, Gentaur ensures that our product range remains relevant and versatile, providing you with the tools needed for both current and future projects.

Find us on

Cat	Name
T8-146-T100	Anti-Hu CD184 PE-Cy1535
T8-138-T100	Anti-Hu CD15 PE-Cy1535
T8-183-T100	Anti-Hu CD7 PE-Cy1535
T8-207-T025	Anti-Hu CD8 PE-Cy1535
T8-209-T025	Anti-Hu CD10 PE-Cy1535
T8-231-T100	Anti-Hu CD56 PE-Cy1535
T8-273-T025	Anti-Hu CD31 PE-Cy1535
T8-308-T100	Anti-Hu CD27 PE-Cy1535
T8-320-C100	Anti-Hu IgM PE-Cy1535
T8-343-T025	Anti-Hu CD63 PE-Cy1535