Anti-Ms CD41 Purified Low Endotoxin

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Alternative Products

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MBS1801391-02	Anti-Ms CD41 Purified
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MBS1801392-01	Anti-Ms CD41 Purified Low Endotoxin
MBS1801392-02	Anti-Ms CD41 Purified Low Endotoxin
MBS1801393-01	Anti-Ms CD41 PE
MBS1801393-02	Anti-Ms CD41 PE
E16FHU0411-100U	Purified anti-human CD41
E16FHU0411-500U	Purified anti-human CD41
MBS1800976-02	Anti-Hu CD41 Purified
MBS1800976-01	Anti-Hu CD41 Purified

CAT:

270-12-763-C100

Size:

0.1 mg

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Anti-Ms CD41 Purified Low Endotoxin

Background: CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
Specifications: The rat monoclonal antibody MWReg30 recognizes an extracellular epitope of CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain 120 kDa) and GPIIb beta (light chain 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
Certification: RUO
Host: Rat
Species Reactivity: Mouse
Immunogen: Murine platelets
Target Antigen: CD41
Isotype: Igg1 κ
Clone: MWReg30
Applications: Functional application: Platelet depletion. Flow cytometry: Recommended dilution: 1-4 µg/mL
Validated Applications: FC, IP, IHC-P, IHC-F, ELISA, Functional assays
Concentration: 1 mg/mL
Format: Purified Low Endotoxin
Buffer: Phosphate buffered saline (PBS), pH 7.4
References & Citations: *Ramsey H, Zhang Q, Brown DE, Steensma DP, Lin CP, Wu MX: Stress-induced hematopoietic failure in the absence of immediate early response gene X-1. Haematologica. 2013 Sep 20. [Epub ahead of print], URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=ramsey+h+steensma+dp ,*Sullivan BP, Wang R, Tawfik O, Luyendyk JP: Protective and damaging effects of platelets in acute cholestatic liver injury revealed by depletion and inhibition strategies. Toxicol Sci. 2010 May115(1):286-94., URL: http://www.ncbi.nlm.nih.gov/pubmed/20133375 ,*Boisset JC, Clapes T, Van Der Linden R, Dzierzak E, Robin C: Integrin 945IIb (CD41) plays a role in the maintenance of hematopoietic stem cell activity in the mouse embryonic aorta. Biol Open. 2013 Apr 112(5):525-32., URL: http://www.ncbi.nlm.nih.gov/pubmed/23789102 ,*Brancaleone V, Gobbetti T, Cenac N, le Faouder P, Colom B, Flower RJ, Vergnolle N, Nourshargh S, Perretti M: A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation. Blood. 2013 Jul 25122(4):608-17., URL: https://pubmed.ncbi.nlm.nih.gov/23733341/,
Storage Conditions: Store at 2-8°C. Do not freeze.

Complementary Product Range

Our range of products, including Anti-Ms CD41 Purified Low Endotoxin, falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

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Cat	Name
11-763-C100	Anti-Ms CD41 Purified
11-763-C025	Anti-Ms CD41 Purified
12-763-C100	Anti-Ms CD41 Purified Low Endotoxin
1P-763-C100	Anti-Ms CD41 PE
1P-763-C025	Anti-Ms CD41 PE
11-309-C025	Anti-Hu CD41 Purified
11-309-C100	Anti-Hu CD41 Purified
11-569-C025	Anti-Ms Bim Purified
11-579-C025	Anti-Ms CD8a Purified
11-580-C025	Anti-Ms CD4 Purified