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Cetrimonium (bromide)

CAT: 0804-HY-B1260-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1260-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cetrimonium bromide (CTAB), a quaternary ammonium, is an orally active cationic surfaetant. Cetrimonium bromide has toxicity and anticancer effect. Cetrimonium bromide inhibits cell migration and invasion through modulating the canonical and non-canonical TGF-β signaling pathways. Cetrimonium bromide can be used for DNA extraction[1][2][3][4].
CAS Number
57-09-0
Product Name Alternative
CTAB; Cetyltrimethylammonium (bromide) ; Hexadecyltrimethylammonium (bromide)
UNSPSC
12352211
Hazard Statement
H302, H315, H318, H335, H373, H410
Target
Apoptosis; Biochemical Assay Reagents; MMP; TGF-β Receptor
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others; TGF-beta/Smad
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Cetrimonium-bromide.html
Purity
98.0
Solubility
DMSO : 10 mg/mL (ultrasonic) |H2O : 4.55 mg/mL (ultrasonic)
Smiles
CCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-]
Molecular Formula
C19H42BrN
Molecular Weight
364.45
Precautions
H302, H315, H318, H335, H373, H410
References & Citations
[1]Wu T K, et al. Cetrimonium bromide inhibits cell migration and invasion of human hepatic SK-HEP-1 cells through modulating the canonical and non-canonical TGF-β signaling pathways [J]. Anticancer research, 2019, 39 (7) : 3621-3631.|[2]Ito E, et al. Potential use of cetrimonium bromide as an apoptosis-promoting anticancer agent for head and neck cancer [J]. Molecular pharmacology, 2009, 76 (5) : 969-983.|[3]Isomaa B, et al. The subacute and chronic toxicity of cetyltrimethylammonium bromide (CTAB), a cationic surfactant, in the rat [J]. Archives of toxicology, 1976, 35: 91-96.|[4]Allen G C, et al. A modified protocol for rapid DNA isolation from plant tissues using cetyltrimethylammonium bromide [J]. Nature protocols, 2006, 1 (5) : 2320-2325.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MMP-2; MMP-9

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