Anti-Hu CD41b Purified

• Description:

  CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.

• Certification:

  RUO

• Target Antigen:

  CD41b

• Clone:

  HIP2

• Applications:

  FC (QC tested), IHC-F

• Concentration:

  1 mg/mL

• Format:

  Purified

• Buffer:

  Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

• Storage Conditions:

  Store at 2-8°C. Do not freeze.

• Specificity:

  The antibody HIP2 reacts with an extracellular epitope on beta (b) subunit of CD41 glycoprotein (light chain; 23 kDa) . CD41 is mainly expressed on platelets and megakaryocytes.

• Applications Notes:

  Flow cytometry: Recommended dilution: 1-4 µg/ml

• Species:

  Non-human primates, Human

• CAS Number:

  9007-83-4

• Isotype:

  Mouse IgG3