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Anti-Hu CD41b Purified

CAT: 0270-11-418-C100Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0270-11-418-C100Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
Certification
RUO
Reactivity
Non-human primates, Human
Target Antigen
CD41b
Clone
HIP2
Applications
FC (QC tested), IHC-F
Concentration
1 mg/mL
Format
Purified
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
The antibody HIP2 reacts with an extracellular epitope on beta (b) subunit of CD41 glycoprotein (light chain; 23 kDa) . CD41 is mainly expressed on platelets and megakaryocytes.
Applications Notes
Flow cytometry: Recommended dilution: 1-4 µg/ml
Isotype
Mouse IgG3