Anti-hTSH Purified

Anti-hTSH Purified

• Background: Thyrotropin (hTSH) promotes the growth of the thyroid gland in the neck and stimulates it to produce more thyroid hormones. hTSH is composed of two subunits - alpha nad beta.
• Specifications: The antibody TSH-51 reacts with human thyroid stimulating hormone (hTSH, thyrotropin), a glycoprotein hormone produced by the anterior pituitary gland cells in response to signals from the hypothalamus gland in the brain. The TSH-51 antibody reacts with association constant 5.5 x 1010 l/mol. Following cross-reactivity expressed as binding of labelled hormone (% of total) was determined by solid phase RIA with excess of the antibody TSH-51: hTSH (68.6), hCG (0.03), hLH (2.99), hFSH (0.66).
• CAS Number: 9007-83-4
• Certification: RUO
• Host: Mouse
• Species Reactivity: Human
• Immunogen: Human thyrotropin.
• Target Antigen: hTSH
• Isotype: IgG2a
• Clone: TSH-51
• Applications: RIA: The antibody TSH-51 is suitable in combination with the antibody TSH-116 for immunometric assays in the screening of neonatal hypothyroidism.
• Validated Applications: ICC, ELISA, RIA
• Concentration: 1 mg/mL
• Format: Purified
• Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• References & Citations: *Jirkalová V, Čáp J, Straková H, Přibyšová J, Plicka J, Lomský R: Immunoradiometric and luminescence immunoenzymometric assay of human thyrotropin from dried blood spots for screening of neonatal hypothyroidism. Eur J Clin Chem Clin Biochem. 1996 Oct34(10):823-7., URL: https://pubmed.ncbi.nlm.nih.gov/8933106/,
• Storage Conditions: Store at 2-8°C. Do not freeze.