Pyronaridine (tetraphosphate)
CAT:
804-HY-14749A-01
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Pyronaridine (tetraphosphate)
- CAS Number: 76748-86-2
- UNSPSC Description: Pyronaridine tetraphosphate is an orally active Mannich base anti-malarial agent. Pyronaridine tetraphosphate is active against P. falciparum and Echinococcus granulosus infection[1][2].
- Target Antigen: Parasite
- Type: Reference compound
- Related Pathways: Anti-infection
- Applications: COVID-19-immunoregulation
- Field of Research: Infection; Cancer
- Assay Protocol: https://www.medchemexpress.com/Pyronaridine_tetraphosphate.html
- Solubility: DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 25 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: OC1=C(CN2CCCC2)C=C(NC3=C4N=C(OC)C=CC4=NC5=CC(Cl)=CC=C53)C=C1CN6CCCC6.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O
- Molecular Weight: 910.03
- References & Citations: [1]Vivas L, et al. Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo. Acta Trop. 2008 Mar;105(3):222-8.|[2]Jun Li, et al. Old drug repurposing for neglected disease: Pyronaridine as a promising candidate for the treatment of Echinococcus granulosus infections. EBioMedicine. 2020 Apr;54:102711.
- Shipping Conditions: Room Temperature
- Clinical Information: Launched