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Allocholic acid

CAT: 0804-HY-125934-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-125934-01Size:1 mg
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Description
Allocholic acid is a typically fetal bile acid found in vertebrates and reappears during liver regeneration and carcinogenesis, besides it is also a conjugate acid of allocholate and an isomer of cholic acid. Allocholic acid is a potent and specific stimulant of the adult olfactory system, it has a role as a marine metabolite, a rat metabolite and a human metabolite[1][2][3].
CAS Number
2464-18-8
UNSPSC
12352211
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/allocholic-acid.html
Purity
99.76
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
C[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C
Molecular Formula
C24H40O5
Molecular Weight
408.57
References & Citations
[1]ThomasBriggs, et al. Allocholic acid, the major component in bile from the river carpsucker, Carpiodes carpio (Rafinesque) (Catostomidae) . Comp Biochem Physiol B. 1972 Jul 15;42 (3) :493-6.|[2]Li W, et al. The olfactory system of migratory adult sea lamprey (Petromyzon marinus) is specifically and acutely sensitive to unique bile acids released by conspecific larvae. J Gen Physiol. 1995 May;105 (5) :569-87.|[3]Mendoza ME, et al. Physiological characteristics of allo-cholic acid. J Lipid Res. 2003 Jan;44 (1) :84-92.|[4]Ridlon JM, et al. Isolation and characterization of a bile acid inducible 7alpha-dehydroxylating operon in Clostridium hylemonae TN271. Anaerobe. 2010 Apr;16 (2) :137-46.|[5]Elliott WH, Hyde PM. Metabolic pathways of bile acid synthesis. Am J Med. 1971 Nov;51 (5) :568-79.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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