CAL-130 (Hydrochloride)

CAL-130 (Hydrochloride)

• CAS Number: 1431697-78-7
• UNSPSC Description: CAL-130 is a PI3Kδ and PI3Kγ inhibitor with IC50s of 1.3 and 6.1 nM, respectively.
• Target Antigen: PI3K
• Type: Reference compound
• Related Pathways: PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cal-130-hydrochloride.html
• Solubility: DMSO : 50 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=C1N(C2=CC=CC=C2C)C([C@H](C)NC3=C4N=CNC4=NC(N)=N3)=NC5=C1C(C)=CC=C5.[H]Cl
• Molecular Weight: 462.93
• References & Citations: [1]Subramaniam Prem S, et al. Targeting nonclassical oncogenes for therapy in T-ALL. Cancer cell (2012), 21(4), 459-72.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported