PythiDC

PythiDC

• CAS Number: 1821370-71-1
• UNSPSC Description: PythiDC is a selective collagen prolyl 4-hydroxylase (CP4H1) inhibitor with an IC50 value of 4.0 μM. PythiDC can be used as a CP4H probe and also can be used for the development of a new class of antifibrotic and antimetastatic agents[1].
• Target Antigen: MMP
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/pythidc.html
• Purity: 99.33
• Solubility: DMSO : 4.9 mg/mL (ultrasonic;warming;adjust pH to 4 with HCl;heat to 60°C)
• Smiles: O=C(C1=CC=C(C2=NC=C(C(O)=O)S2)N=C1)O
• Molecular Weight: 250.23
• References & Citations: [1]Vasta JD, et al. Selective Inhibition of Collagen Prolyl 4-Hydroxylase in Human Cells. ACS Chem Biol. 2016 Jan 15;11(1):193-9.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported