PythiDC

• UNSPSC Description:

  PythiDC is a selective collagen prolyl 4-hydroxylase (CP4H1) inhibitor with an IC50 value of 4.0 μM. PythiDC can be used as a CP4H probe and also can be used for the development of a new class of antifibrotic and antimetastatic agents[1].

• Target Antigen:

  MMP

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/pythidc.html

• Purity:

  99.33

• Solubility:

  DMSO : 4.9 mg/mL (ultrasonic;warming;adjust pH to 4 with HCl;heat to 60°C)

• Smiles:

  O=C(C1=CC=C(C2=NC=C(C(O)=O)S2)N=C1)O

• Molecular Weight:

  250.23

• References & Citations:

  [1]Vasta JD, et al. Selective Inhibition of Collagen Prolyl 4-Hydroxylase in Human Cells. ACS Chem Biol. 2016 Jan 15;11(1):193-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1821370-71-1