PythiDC

• Description :

  PythiDC is a selective collagen prolyl 4-hydroxylase (CP4H1) inhibitor with an IC50 value of 4.0 μM. PythiDC can be used as a CP4H probe and also can be used for the development of a new class of antifibrotic and antimetastatic agents[1].

• UNSPSC :

  12352005

• Target :

  MMP

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/pythidc.html

• Purity :

  99.05

• Solubility :

  DMSO : 4.9 mg/mL (ultrasonic; warming; adjust pH to 4 with HCl; heat to 60°C)

• Smiles :

  O=C(C1=CC=C(C2=NC=C(C(O)=O)S2)N=C1)O

• Molecular Formula :

  C10H6N2O4S

• Molecular Weight :

  250.23

• References & Citations :

  [1]Vasta JD, et al. Selective Inhibition of Collagen Prolyl 4-Hydroxylase in Human Cells. ACS Chem Biol. 2016 Jan 15;11 (1) :193-9.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1821370-71-1]