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Lignoceric acid-d4

CAT: 0804-HY-121883S2Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-121883S2Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lignoceric acid-d4 (Tetracosanoic acid-d4) is deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2][1][2][3].
CAS Number
61389-26-2
Product Name Alternative
Tetracosanoic acid-d4
UNSPSC
12352211
Target
Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
CCCCCCCCCCCCCCCCCCCC([2H])([2H])CC([2H])([2H])CC(O)=O
Molecular Formula
C24H44D4O2
Molecular Weight
372.66
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Anna Petroni, et al. Thermogenic flux induced by lignoceric acid in peroxisomes isolated from HepG2 cells and from X-adrenoleukodystrophy and control fibroblasts. J Cell Physiol. 2019 Aug;234 (10) :18344-18348.|[3]J M Bourre, et al. Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-CoA-dependent synthesis and microsomal malonyl-CoA chain-elongating system in relation to myelination. Comparison between normal mouse and dysmyelinating mutants (quaking and jimpy) . Eur J Biochem. 1977 Jan 3;72 (1) :41-7.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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