Lignoceric acid-d4

• Description:

  Lignoceric acid-d4 (Tetracosanoic acid-d4) is deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2][1][2][3].

• Product Name Alternative:

  Tetracosanoic acid-d4

• UNSPSC:

  12352211

• Target:

  Endogenous Metabolite; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Metabolic Enzyme/Protease; Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Smiles:

  CCCCCCCCCCCCCCCCCCCC([2H])([2H])CC([2H])([2H])CC(O)=O

• Molecular Formula:

  C24H44D4O2

• Molecular Weight:

  372.66

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Anna Petroni, et al. Thermogenic flux induced by lignoceric acid in peroxisomes isolated from HepG2 cells and from X-adrenoleukodystrophy and control fibroblasts. J Cell Physiol. 2019 Aug;234 (10) :18344-18348.|[3]J M Bourre, et al. Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-CoA-dependent synthesis and microsomal malonyl-CoA chain-elongating system in relation to myelination. Comparison between normal mouse and dysmyelinating mutants (quaking and jimpy) . Eur J Biochem. 1977 Jan 3;72 (1) :41-7.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  [61389-26-2]