Lignoceric acid-d3

CAT: 0804-HY-121883S1Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-121883S1Size:5 mg
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Description
Lignoceric acid-d3 is the deuterium labeled Lignoceric acid[1]. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[2][3].
CAS Number
[851073-55-7]
Product Name Alternative
Tetracosanoic acid-d3
UNSPSC
12352211
Hazard Statement
H315, H319
Target
Endogenous Metabolite
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
99.00
Solubility
THF : 5 mg/mL (ultrasonic; warming)
Smiles
[2H]C([2H])([2H])CCCCCCCCCCCCCCCCCCCCCCC(O)=O
Molecular Formula
C24H45D3O2
Molecular Weight
371.66
Precautions
H315, H319
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Anna Petroni, et al. Thermogenic flux induced by lignoceric acid in peroxisomes isolated from HepG2 cells and from X-adrenoleukodystrophy and control fibroblasts. J Cell Physiol. 2019 Aug;234 (10) :18344-18348.|[3]J M Bourre, et al. Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-CoA-dependent synthesis and microsomal malonyl-CoA chain-elongating system in relation to myelination. Comparison between normal mouse and dysmyelinating mutants (quaking and jimpy) . Eur J Biochem. 1977 Jan 372 (1) :41-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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