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S35D1 rabbit pAb

CAT: 0855-ES13240-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES13240-01Size:50 µL
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Background
Glycosylation of cellular glycoconjugates occurs in the endoplasmic reticulum (ER) and Golgi compartment, and requires transport of nucleotide sugars from the cytosol into the lumen of the ER and Golgi by specific transporters. The protein encoded by this gene resides in the ER, and transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to the ER lumen. It may participate in glucuronidation and/or chondroitin sulfate biosynthesis. Mutations in this gene are associated with Schneckenbecken dysplasia.[provided by RefSeq, Sep 2009]
Description
Glycosylation of cellular glycoconjugates occurs in the endoplasmic reticulum (ER) and Golgi compartment, and requires transport of nucleotide sugars from the cytosol into the lumen of the ER and Golgi by specific transporters. The protein encoded by this gene resides in the ER, and transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to the ER lumen. It may participate in glucuronidation and/or chondroitin sulfate biosynthesis. Mutations in this gene are associated with Schneckenbecken dysplasia. [provided by RefSeq, Sep 2009],
Product Name Alternative
UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter (UDP-GlcA/UDP-GalNAc transporter) (Solute carrier family 35 member D1) (UDP-galactose transporter-related protein 7) (UGTrel7)
UniProt
Q9NTN3
Swiss Prot
Q9NTN3
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human S35D1 AA range: 91-141
Target
S35D1
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Molecular Weight
38kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
38kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Other Product Names
UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter (UDP-GlcA/UDP-GalNAc transporter) (Solute carrier family 35 member D1) (UDP-galactose transporter-related protein 7) (UGTrel7)
Gene ID (Human)
23169

UniProtKB · Q9NTN3

Nucleotide sugar transporter SLC35D1

S35D1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NTN3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC35D1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K185, B7Z3X2, Q52LU5, Q92548
Protein keywords

Coding sequence diversity

Alternative splicing

Disease

Disease variantDwarfism

Cellular component

Endoplasmic reticulumMembrane

Technical term

Proteomics identificationReference proteome

Biological process

Sugar transportTransport

Domain

TransmembraneTransmembrane helix

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