Propofol

CAT: 0804-HY-B0649-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0649-01Size:100 mg
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Description
Propofol potently and directly activates GABAA receptor and inhibits glutamate receptor mediated excitatory synaptic transmission. Propofol has antinociceptive properties and is used for sedation and hypnotic[1].
CAS Number
[2078-54-8]
Product Name Alternative
2,6-Diisopropylphenol
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/propofol.html
Concentration
10mM
Purity
99.52
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 0.5 mg/mL (ultrasonic)
Smiles
OC1=C(C(C)C)C=CC=C1C(C)C
Molecular Formula
C12H18O
Molecular Weight
178.27
Precautions
H302, H315, H319, H335
References & Citations
[1]R Nadeson, et al. Antinociceptive Properties of Propofol: Involvement of Spinal Cord Gamma-Aminobutyric acid (A) Receptors. J Pharmacol Exp Ther . 1997 Sep;282 (3) :1181-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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