Propofol

• UNSPSC Description:

  Propofol potently and directly activates GABAA receptor and inhibits glutamate receptor mediated excitatory synaptic transmission. Propofol has antinociceptive properties and is used for sedation and hypnotic[1].

• Target Antigen:

  Endogenous Metabolite; GABA Receptor

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/propofol.html

• Purity:

  99.52

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)|H2O : 0.5 mg/mL (ultrasonic)

• Smiles:

  OC1=C(C(C)C)C=CC=C1C(C)C

• Molecular Weight:

  178.27

• References & Citations:

  [1]R Nadeson, et al. Antinociceptive Properties of Propofol: Involvement of Spinal Cord Gamma-Aminobutyric acid(A) Receptors. J Pharmacol Exp Ther . 1997 Sep;282(3):1181-6.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  Launched

• CAS Number:

  2078-54-8