Products for Research Use Only
RegisterLogin

Dacarbazine (Standard)

CAT: 0804-HY-B0078R-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B0078R-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Dacarbazine (Standard) is the analytical standard of Dacarbazine. This product is intended for research and analytical applications. Dacarbazine is a nonspecific antineoplastic (antineoplastic) alkylating agent. Dacarbazine inhibits T and B lymphocyte responses with IC50 of 50 and 10 μg/mL, respectively. Dacarbazine can be used in the study of metastatic malignant melanoma[1][2][1][2][3][4].
CAS Number
4342-03-4
Product Name Alternative
Imidazole Carboxamide (Standard)
UNSPSC
12352005
Target
Apoptosis; Nucleoside Antimetabolite/Analog; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dacarbazine-standard.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(/N=N/N(C)C)NC=N1)N
Molecular Formula
C6H10N6O
Molecular Weight
182.18
References & Citations
[1]Erdmann S, et al. Induced cross-resistance of BRAFV600E melanoma cells to standard chemotherapeutic dacarbazine after chronic PLX4032 treatment. Sci Rep. 2019 Jan 10;9 (1) :30.|[2]Salvador D, et al. Combined Therapy with Dacarbazine and Hyperthermia Induces Cytotoxicity in A375 and MNT-1 Melanoma Cells. Int J Mol Sci. 2022 Mar 25;23 (7) :3586.|[3]Serrone, L., et al., Dacarbazine-based chemotherapy for metastatic melanoma: thirty-year experience overview. J Exp Clin Cancer Res, 2000. 19 (1) : p. 21-34.|[4]Al-Badr AA, et al. Dacarbazine. Profiles Drug Subst Excip Relat Methodol. 2016;41:323-77.|[5]Rojo JM, et al. Inhibition of T and B lymphoblastic response by mithramycin, dacarbazine, prospidium chloride and peptichemio. Chemotherapy. 1983;29 (5) :345-51.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
Launched

Related Products

CatalogName
HY-B0078-01Dacarbazine
HY-B0078SDacarbazine-d6
HY-B0078BDacarbazine (hydrochloride)
HY-B0078ADacarbazine (citrate)
HY-P2274RArgifin (Standard)
HY-N9362REmodinanthrone (Standard)
HY-N7948RIsomaltotetraose (Standard)
HY-N7640RDeoxylimonin (Standard)
HY-N7617RToralactone (Standard)
HY-N7541RAntrodin A (Standard)

Alternative Products

CatalogName
FD01582-01Dacarbazine

Popular Products