Anti-PD-1 [11F5C5]

Anti-PD-1 [11F5C5]

• Gene Name: [PD-1]
• NCBI Gene ID: 5133
• Reactivity: Human
• Storage Conditions: Store at 4 °C for up to 3 months. For longer storage, aliquot and store at -20 °C.
• Specificity: This antibody binds the extracellular domain of the human PD-1. PD-1 is an immunosuppressive receptor having a molecular weight of 50 to 55 kD, a type 1 transmembrane glycoprotein belonging to immunoglobulin CD28/CTLA-4 family members. It is an inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self. It delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2.
• Other Gene Names: [PDCD1; PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; PD1; Protein PD-1; hPD-1]
• Short Name: [PD-1]
• Other Product Names: [Programmed cell death protein 1; Programmed cell death protein 1; programmed cell death protein 1; programmed cell death 1; CD_antigen: CD279]
• NCBI GI Number: 145559515
• NCBI Accession Number: Q15116.3
• Uniprot Accession Number: Q15116