Anti-Canine PD-1

• Description:

  Mouse Monoclonal Antibody specific to Canine PD-1

• Product Name Alternative:

  Anti-Canine PD-1 Mouse Monoclonal Antibody

• Host:

  Mouse

• Reactivity:

  Canine

• Immunogen:

  Recombinant extracellular domain of canine PD-1 fused with the Fc domain of human IgG1 expressed in D. melanogaster S2 cells.

• Target:

  Canine PD-1

• Clonality:

  Monoclonal

• Isotype:

  IgA

• Type:

  Antibody

• Applications:

  IHC, FACS, Inhibition

• Purification Method:

  PEG Purified

• Concentration:

  Lot Specific

• Dilution:

  Dilute in PBS or medium that is identical to that used in the assay system.

• Format:

  Purified

• Form:

  Liquid

• Buffer:

  Phosphate Buffered Saline

• Additionnal Information:

  Canine PD-1 Monoclonal Antibody Flow cytometry Detection of PD-1 expression on CLGL-90 cells (Chronic Large Granular Lymphocytic-90) stained with JC053 (dark gray) vs. mouse IgA isotype control (light gray). Inhibition of PD-1 and PD-L1 Interaction JC053 antibody added to ELISA plates coated with PD-1 followed by the addition of biotinylated PD-L1and streptavidin-HRP. JC053 antibody blocked binding of PD-1 to PD-L1 as compared with binding of PD-1 to PD-L1 in the presence of a non-inhibitory antibody 73H2.
  
  End users should determine optimal antibody concentrations for their applications.

• Storage Conditions:

  This antibody is stable for at least one (1) year at -20°C to-70°C. Store in appropriate aliquots to avoid multiple freeze-thaw cycles.

• Specificity:

  This antibody recognizes canine PD-1.

• Formulation:

  PBS, pH 7.4.

• Buffer pH:

  pH 7.4

• CAS Number:

  9007-83-4