DPCPX

• Description :

  DPCPX (PD 116948), a xanthine derivative, is a highly potent and selective Adenosine A1 receptor antagonist, with a Ki of 0.46 nM in 3H-CHA binding to A1 receptors in rat whole brain membranes[1][2][3].

• Product Name Alternative :

  PD 116948

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Adenosine Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/dpcpx.html

• Concentration :

  10mM

• Purity :

  99.96

• Solubility :

  DMSO : 10 mg/mL (ultrasonic)

• Smiles :

  O=C(N1CCC)N(CCC)C2=C(N=C(C3CCCC3)N2)C1=O

• Molecular Formula :

  C16H24N4O2

• Molecular Weight :

  304.39

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]S J Haleen, et al. PD 116,948, a Highly Selective A1 Adenosine Receptor Antagonist. Life Sci. 1987 Feb 9;40 (6) :555-61.|[2]R F Bruns, et al. Binding of the A1-selective Adenosine Antagonist 8-cyclopentyl-1,3-dipropylxanthine to Rat Brain Membranes. Naunyn Schmiedebergs Arch Pharmacol. 1987 Jan;335 (1) :59-63.|[3]POSTER COMMUNICATIONS Part II. Br J Pharmacol. 1989 Jul; 97 (Suppl) : 496P–535P.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [102146-07-6]