1-Octanol-d2
CAT:
804-HY-W032013S1
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
1-Octanol-d2
- CAS Number: 78510-02-8
- UNSPSC Description: 1-Octanol-d2 is the deuterium labeled 1-Octanol[1]. 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents[2]. 1-Octanol is a highly attractive biofuel with diesel-like properties[3].
- Target Antigen: Calcium Channel; Endogenous Metabolite
- Type: Isotope-Labeled Compounds
- Related Pathways: Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Metabolic Disease
- Solubility: 10 mM in DMSO
- Smiles: CCCCCCCC([2H])([2H])O
- Molecular Weight: 132.24
- References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Joksovic PM, et al. Mechanisms of inhibition of T-type calcium current in the reticular thalamic neurons by 1-octanol: implication of the protein kinase C pathway. Mol Pharmacol. 2010 Jan;77(1):87-94.|[3]Akhtar MK, et al. Microbial production of 1-octanol: A naturally excreted biofuel with diesel-like properties. Metab Eng Commun. 2014 Nov 132:1-5.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported