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1-Octanol-d2

CAT: 0804-HY-W032013S1-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W032013S1-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
1-Octanol-d2 is the deuterium labeled 1-Octanol[1]. 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents[2]. 1-Octanol is a highly attractive biofuel with diesel-like properties[3].
CAS Number
78510-02-8
Product Name Alternative
Octanol-d2
UNSPSC
12352211
Target
Calcium Channel; Endogenous Metabolite
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Purity
99.0
Solubility
10 mM in DMSO
Smiles
CCCCCCCC([2H])([2H])O
Molecular Formula
C8H16D2O
Molecular Weight
132.24
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Joksovic PM, et al. Mechanisms of inhibition of T-type calcium current in the reticular thalamic neurons by 1-octanol: implication of the protein kinase C pathway. Mol Pharmacol. 2010 Jan;77 (1) :87-94.|[3]Akhtar MK, et al. Microbial production of 1-octanol: A naturally excreted biofuel with diesel-like properties. Metab Eng Commun. 2014 Nov 132:1-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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