1-Octanol

• Description:

  1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents[1]. 1-Octanol is a highly attractive biofuel with diesel-like properties[2].

• Product Name Alternative:

  Octanol

• UNSPSC:

  12352211

• Hazard Statement:

  H227, H319, H412

• Target:

  Calcium Channel; Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/1-octanol.html

• Concentration:

  10mM

• Purity:

  99.63

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  OCCCCCCCC

• Molecular Formula:

  C8H18O

• Molecular Weight:

  130.23

• Precautions:

  H227, H319, H412

• References & Citations:

  [1]Joksovic PM, et al. Mechanisms of inhibition of T-type calcium current in the reticular thalamic neurons by 1-octanol: implication of the protein kinase C pathway. Mol Pharmacol. 2010 Jan;77 (1) :87-94.|[2]Akhtar MK, et al. Microbial production of 1-octanol: A naturally excreted biofuel with diesel-like properties. Metab Eng Commun. 2014 Nov 13;2:1-5.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at room temperature 3 years

• Scientific Category:

  Natural Products

• Clinical Information:

  Phase 2

• Isoform:

  Microbial Metabolite; T-type calcium channel

• CAS Number:

  [111-87-5]