RVD-Hpα

• Description :

  RVD-Hpα, an α-hemoglobin-derived peptide containing three additional amino acids, is a CB1 cannabinoid receptor agonist. RVD-Hpα is a positive allosteric modulator of cannabinoid receptor 2[1][2].

• UNSPSC :

  12352209

• Target :

  Cannabinoid Receptor

• Type :

  Peptides

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/rvd-hpα.html

• Solubility :

  10 mM in DMSO

• Smiles :

  N=C(N)NCCC[C@H](N)C(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(N1[C@@H](CCC1)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@H](C(O)=O)CC2=CN=CN2)=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C65H105N19O17

• Molecular Weight :

  1424.65

• References & Citations :

  [1]Ivone Gomes, et al. Novel endogenous peptide agonists of cannabinoid receptors. FASEB J. 2009 Sep;23 (9) :3020-9.|[2]Fengmei Wei, et al. Hemoglobin-derived peptides and mood regulation. Peptides. 2020 Feb 15;127:170268.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• Isoform :

  CB1

• CAS Number :

  [1193362-76-3]