STK17A/B-IN-1

STK17A/B-IN-1

• CAS Number: 3002038-21-0
• UNSPSC Description: STK17A/B-IN-1 (compound 9) is an orally active, potent, and selective STK17A/B inhibitor with an IC50 of 23 nM against STK17A. STK17A/B-IN-1 can be used for study of cancer[1].
• Target Antigen: DAPK
• Type: Reference compound
• Related Pathways: Apoptosis
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/stk17a-b-in-1.html
• Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=C(C1=CC=C(NC2=NC=CC(C3=CC4=C(N=C(N5CCCC5)N=C4)C=C3)=N2)C=C1)NC(C)C
• Molecular Weight: 453.54
• References & Citations: [1]Chaudhry S, et al. Potent, Selective, and Orally Bioavailable Quinazoline-Based STK17A/B Dual Inhibitors. ACS Med Chem Lett. 2024;15(6):945-949. Published 2024 May 20.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported