Glutamine Synthetase Recombinant Mouse Monoclonal Antibody [A3G2-R]

Glutamine Synthetase Recombinant Mouse Monoclonal Antibody [A3G2-R]

• Description: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.
• Product Name Alternative: cell proliferation-inducing protein 59 antibody Cgl2214 antibody GLNA antibody GLNA_HUMAN antibody GLNS antibody GLUL antibody Glutamate ammonia ligase antibody Glutamate decarboxylase antibody Glutamate--ammonia ligase antibody glutamine synthase antibody Glutamine synthetase antibody glutamine synthetase I antibody GS antibody PIG 43 antibody PIG 59 antibody PIG43 antibody PIG59 antibody Proliferation inducing protein 43 antibody
• Abbreviation: GLUL
• CAS Number: 9000-83-3
• Swiss Prot: P15104 Human, P15105 Mouse, P09606 Rat
• Cellular Locus: Microsome, Cytosol, Mitochondrion, Cell membrane.
• Host: Mouse
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within human Glutamine synthetase aa 190-373.
• Isotype: IgG1
• Clone: A3G2-R
• Conjugation: Non-conjugated
• Type: Recombinant Mouse monoclonal Antibody
• Applications: WB, IHC-P
• Positive Control: HeLa cell lysate, MCF7 cell lysate, HepG2 cell lysate, K-562 cell lysate, Jurkat cell lysate, HEK-293 cell lysate, SK-Br-3 cell lysate, human liver tissue lysate, human spleen tissue, mouse liver tissue, rat liver tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:2,000 ;IHC-P: 1:500-1:2,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 42 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes