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Clascoterone-d5

CAT: 0804-HY-W759404-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W759404-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Clascoterone-d5 (Cortexolone 17 alpha-propionate-d5) is the deuterated analog of Clascoterone. Clascoterone is a topical and peripheral androgen antagonist[1][2][3].
Product Name Alternative
Cortexolone 17 alpha-propionate-d5; Cortexolone 17α-propionate-d5; CB-03-01-d5
UNSPSC
12352211
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Purity
95.0
Solubility
10 mM in DMSO
Smiles
O=C1CC[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@](CC[C@@]4([H])[C@]3([H])CCC2=C1)(C(CO)=O)OC(C(C([2H])([2H])[2H])([2H])[2H])=O
Molecular Formula
C24H29D5O5
Molecular Weight
407.55
References & Citations
[1]Trifu V, et al. Cortexolone 17-propionate 1% cream, a new potent antiandrogen for topical treatment of acne vulgaris. A pilot randomized, double-blind comparative study vs. placebo and tretinoin 005% cream. Br J Dermatol. 2011 Jul;165 (1) :177-83.|[2]Trifu V, et al. Cortexolone 17α-propionate 1% cream, a new potent antiandrogen for topical treatment of acne vulgaris. A pilot randomized, double-blind comparative study vs. placebo and tretinoin 0·05% cream. Br J Dermatol. 2011 Jul;165 (1) :177-83.|[3]Celasco G, et al. Biological profile of cortexolone 17alpha-propionate (CB-03-01), a new topical and peripherally selective androgen antagonist. Arzneimittelforschung. 2004;54 (12) :881-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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