Leucovorin-d4 (calcium hydrate), >90%

• UNSPSC Description:

  Leucovorin-d4 (Leucovorin-d4) calcium hydrate, >90% is a deuterated labeled Folinic acid (Leucovorin, HY-17556). Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity[1].

• Target Antigen:

  Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C2=C(NC(N)=N1)NC(C([2H])(N2C=O)C([2H])(NC3=CC=C(C=C3)C(N[C@@H](CCC([O-])=O)C([O-])=O)=O)[2H])[2H].[Ca+2].O

• Molecular Weight:

  533.54

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

• Shipping Conditions:

  Room temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported