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Yoshi-864

CAT: 0804-HY-129762Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-129762Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Yoshi-864 (NSC-102627) is an alkylsulfonate DNA crosslinker with anticancer activity. Yoshi-864 extends markedly the survival times of mice bearing L1210 leukemia or Ehrlich ascites carcinoma. Yoshi-864 also has a persistent reduction in ability to synthesize DNA in tumor cells from mice bearing the Ehrlich tumor[1].
CAS Number
3458-22-8
Product Name Alternative
NSC-102627
UNSPSC
12352211
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/yoshi-864.html
Smiles
CS(=O)(OCCCNCCCOS(C)(=O)=O)=O.[H]Cl
Molecular Formula
C8H20ClNO6S2
Molecular Weight
325.83
References & Citations
[1]Gale GR, et al. Comparative effects of Yoshi-864 and busulfan on certain transplantable murine tumors. Proc Soc Exp Biol Med. 1975 May;149 (1) :98-101.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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