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ANS

CAT: 0804-HY-D0896-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0804-HY-D0896-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ANS (8-Anilino-1-naphthalenesulfonic acid) is a competitive inhibitor targeting thyroxine binding globulin (TBG) (Ki=2.09x106 M-1) . ANS is used in radioimmunoassay by displacing bound triiodothyronine (T3) to improve detection sensitivity. ANS can block the protein binding site of T3 and release free T3 for antibody recognition. As a fluorescent probe, ANS can specifically bind to the hydrophobic region of proteins (such as membrane proteins) and monitor the dynamics of protein conformation through changes in fluorescent signals. It is widely used in biochemical research and antibacterial material development[1][2].
CAS Number
82-76-8
Product Name Alternative
ANSA; 8-Anilino-1-naphthalenesulfonic acid
UNSPSC
12352200
Hazard Statement
H315, H319
Target
Bacterial
Type
Biochemical Assay Reagents
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ans.html
Purity
98.01
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=S(O)(C1=CC=CC2=CC=CC(NC3=CC=CC=C3)=C21)=O
Molecular Formula
C16H13NO3S
Molecular Weight
299.35
Precautions
H315, H319
References & Citations
[1]Polak J, et al. Bioactive Properties of a Novel Antibacterial Dye Obtained from Laccase-Mediated Oxidation of 8-Anilino-1-naphthalenesulfonic Acid. Molecules. 2022 Jan 13;27 (2) :487.|[2]Brown ML, et al. Use of 8-anilino-1-naphthalenesulfonic acid in radioimmunoassay of triiodothyronine. J Pharm Sci. 1974 Aug;63 (8) :1214-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Biochemical Assay Reagents
Clinical Information
Phase 4

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