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Phospho-PKR (Thr446) Rabbit Polyclonal Antibody

CAT: 0013-GTR17725506-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0013-GTR17725506-01Size:50 μL
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Description
Phospho-PKR (Thr446) Rabbit Polyclonal Antibody
Product Name Alternative
DYT33; EIF2AK1; LEUDEN; PKR; PPP1R83; PRKR; E2AK2_HUMAN; EIF2AK2; Eukaryotic translation initiation factor 2-alpha kinase 2 (eIF-2A protein kinase 2) ; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein kinase; Protein kinase RNA-activated (PKR | Protein kinase R) ; Tyrosine-protein kinase EIF2AK2; p68 kinase; 2.7.11.1; eukaryotic translation initiation factor 2 alpha kinase 2; protein kinase, interferon-inducible double stranded RNA dependent; protein phosphatase 1, regulatory subunit 83; Protein Kinase RNA-activated; protein kinase RNA-regulated; Protein Kinase R; EIF2AK2 | PKR (phospho-T446) ; p-PKR; phospho-PKR; p-EIF2AK2; EIF2AK2 | PKR (phospho-Thr446)
UniProt
P19525
Reactivity
Human, Rat
Immunogen
KLH conjugated Synthesised phosphopeptide derived from human PKR around the phosphorylation site of Thr446 KR (p-T) RS
Target
EIF2AK2
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
Affinity purified by Protein A
Concentration
1mg/ml
Dilution
WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=2ug/Test
Form
Liquid
Molecular Weight
60 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Prediction Reactivity
Mouse
Tested Applications
FC, IF, IHC-Fr, IHC-P, WB
Host or Source
Rabbit
Preservative
0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
Isotype
IgG

UniProtKB · P19525

Interferon-induced, double-stranded RNA-activated protein kinase

E2AK2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P19525
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EIF2AK2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
A8K3P0, D6W584, E9PC80, Q52M43, Q7Z6F6, Q9UIR4
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

Antiviral defenseHost-virus interactionImmunityInnate immunityTranscriptionTranscription regulation

Ligand

ATP-bindingMagnesiumNucleotide-binding

Cellular component

CytoplasmNucleus

Disease

Disease variantDystonia

Molecular function

KinaseRNA-bindingSerine/threonine-protein kinaseTransferaseTyrosine-protein kinase

Domain

Repeat

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