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PKR(Phospho Thr446) Polyclonal Antibody

CAT: 0965-JOT-AP13135-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP13135-01Size:20 µL
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Background
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.
CAS Number
9007-83-4
Synonyms
Interferon-induced double-stranded RNA-activated protein kinase; EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human PKR around the phosphorylation site of Thr446. AA range:413-462
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
62094
Antibody Type
Primary antibody
Isotype
IgG

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