Walrycin B
CAT:
804-HY-18219-05
Size:
25 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Walrycin B
- CAS Number: 878419-78-4
- UNSPSC Description: Walrycin B, an analogue of toxoflavin, is a potent SARS-CoV-2 3CLpro inhibitor with an IC50 of 0.26 μM. Walrycin B is a WalR response regulator inhibitor. Walrycin B has potent activity of inhibiting bacteria growth[1][2].
- Target Antigen: Antibiotic; Bacterial; SARS-CoV
- Type: Reference compound
- Related Pathways: Anti-infection
- Applications: COVID-19-immunoregulation
- Field of Research: Infection; Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/walrycin-b.html
- Purity: 98.38
- Solubility: DMSO : 11.5 mg/mL (ultrasonic;warming)
- Smiles: O=C(C1=NC(C2=CC=C(C(F)(F)F)C=C2)=NN(C)C1=N3)N(C)C3=O
- Molecular Weight: 337.26
- References & Citations: [1]Gotoh Y, et al. Novel antibacterial compounds specifically targeting the essential WalR response regulator. J Antibiot (Tokyo). 2010 Mar;63(3):127-34.|[2]Wei Zhu, et al. Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-throughput Screening. bioRxiv. 2020 Aug 11:2020.07.17.207019.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported