His-Cys-Lys-Phe-Trp-Trp

• UNSPSC Description:

  His-Cys-Lys-Phe-Trp-Trp is an inhibitor for the human immunodeficiency virus (HIV) integrase with an IC50 of 2 μM[1].

• Target Antigen:

  HIV Integrase

• Type:

  Peptides

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/his-cys-lys-phe-trp-trp.html

• Smiles:

  O=C(O)[C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CC3=CNC4=C3C=CC=C4)NC([C@H](CC5=CC=CC=C5)NC([C@H](CCCCN)NC([C@H](CS)NC([C@H](CC6=CNC=N6)N)=O)=O)=O)=O)=O

• Molecular Weight:

  906.06

• References & Citations:

  [1]Puras Lutzke RA, et al., Identification of a hexapeptide inhibitor of the human immunodeficiency virus integrase protein by using a combinatorial chemical library. Proc Natl Acad Sci U S A. 1995 Dec 5;92(25):11456-60.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  172546-75-7