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H-Trp-Phe-OH

CAT: 0804-HY-P4641-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P4641-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
H-Trp-Phe-OH is a dipeptide consisting of tryptophan and phenylalanine (Trp-Phe) . H-Trp-Phe-OH is also an antihypertensive peptide with inhibitory activity on angiotensin-converting enzyme (ACE), dose-dependently increases NO levels, and decreases endothelin-1 (ET-1) levels. H-Trp-Phe-OH (2 mg/kg; subcutaneous injection; 6 injections over 3 days) causes an increase in ovarian weight in female mice[1][2].
CAS Number
6686-02-8
Product Name Alternative
Trp-Phe
UNSPSC
12352209
Target
Angiotensin-converting Enzyme (ACE)
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/h-trp-phe-oh.html
Purity
99.87
Solubility
DMSO : 100 mg/mL
Smiles
OC([C@H](CC1=CC=CC=C1)NC([C@@H](N)CC2=CNC3=CC=CC=C23)=O)=O
Molecular Formula
C20H21N3O3
Molecular Weight
351.40
References & Citations
[1]Zhao YQ, et al. Eight antihypertensive peptides from the protein hydrolysate of Antarctic krill (Euphausia superba) : Isolation, identification, and activity evaluation on human umbilical vein endothelial cells (HUVECs) . Food Res Int. 2019 Jul;121:197-204.|[2]Pitkow et al. Pharmacological effect of dipeptides on ovarian and uterine weights in immature mice. IRCS Medical Science: Library Compendium (1977), 5 (8), 378.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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