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Clorgyline

CAT: 0804-HY-14197-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14197-01Size:5 mg
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Description
Clorgyline (M&B 9302) is an orally active, blood-brain barrier permeable and selective monoamine oxidase A (MAO-A) inhibitor. Clorgyline's selective inhibition of MAO-A leads to reduced metabolism of neurotransmitters such as serotonin (5-hydroxytryptamine), which accumulates in the brain. Clorgyline can be used in the study of depression and neurodegenerative diseases[1].
CAS Number
17780-72-2
Product Name Alternative
M&B 9302
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/clorgyline.html
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC1=CC=C(C(Cl)=C1)OCCCN(CC#C)C
Molecular Formula
C13H15Cl2NO
Molecular Weight
272.17
References & Citations
[1]Knoll J. The possible mechanisms of action of (-) deprenyl in Parkinson's disease[J]. Journal of Neural Transmission, 1978, 43: 177-198.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
Chembiochem. 2025 Oct 28:e202500462.|Biochem Biophys Res Commun. 2022 May 28;606:135-141.|Cell Rep. 2022 Dec 13;41 (11) :111827.|FASEB J. 2021 Jun;35 (6) :e21652.|Immunomedicine. 2022 Dec;2 (2) :e1041.|J Immunother Cancer. 2025 Mar 22;13 (3) :e010555.|Sci Total Environ. 2023 Dec 15:904:166688.

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