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IL-6

CAT: 0426-E21-G39Size: 10 µgDry Ice: NoHazardous: No
CAT#:0426-E21-G39Size:10 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interleukin-6 (IL-6) is a pro-inflammatory cytokine that also has an important role in immunity. Mouse IL-6 appears to be directly involved in the responses that occur after infection and injury and may prove to be as important as IL-1 in regulating the acute phase response. Mouse IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages, and endothelial cells. It acts upon a variety of cells, including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. IL-6 has a wide variety of biological functions: it plays an essential role in the final differentiation of B-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, nerve cells differentiation in hepatocytes, and acute phase reactants.
Description
Recombinant Mouse Interleukin-6 is produced by our E.coli expression system and the target gene encoding Phe25-Thr211 is expressed.
Synonyms
Interleukin-6; IL-6; B-Cell Hybridoma Growth Factor; Interleukin HP-1; Il6; Il-6
Expression System
E. Coli
Endotoxin
Less than 0.1 ng/ µg (1 IEU/ µg) as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Form
Lyophilized
Shipping Conditions
The product is shipped at ambient temperature.
Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl, pH7.4.
Species
Mouse
Shipping Temperature
Ambient

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