IL-1F1/IL-1a

CAT: 0426-E21-070Size: 10 µgDry Ice: NoHazardous: No
CAT#:0426-E21-070Size:10 µg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses.
Description
Recombinant Human Interleukin-1 alpha is produced by our E.coli expression system and the target gene encoding Ser113-Ala271 is expressed.
Synonyms
Interleukin-1 Alpha; IL-1 Alpha; Hematopoietin-1; IL1A; IL1F1
Expression System
E. Coli
Endotoxin
Less than 0.1 ng/ µg (1 IEU/ µg) as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Form
Lyophilized
Shipping Conditions
The product is shipped at ambient temperature.
Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 7.5.
Species
Human
Shipping Temperature
Ambient

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