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SMAD5, Mouse (sf9)

CAT: 0804-HY-P74540Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P74540Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SMAD5 (dwarfin C, JV5-1, MAD5) is a receptor activated Smad (R-Smad) belonging to the dwarfin/SMAD family. SMAD5 protein is activated by TGF-β receptor type I and binds to SMAD4 to form a trimer active form. SMAD5 is involved in BMP signaling pathway, regulates osteogenesis and is related to embryonic development. SMAD5 can up-regulate Runx2 expression and target osteocalcin and alkaline phosphatase (ALP) to function[1]. SMAD5 Protein, Mouse (sf9) has 464 amino acids expressed by sf9 insect cells with tag free.
Product Name Alternative
SMAD5 Protein, Mouse (sf9), Mouse, Sf9 insect cells
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/smad5-protein-mouse-sf9.html
Molecular Formula
17129 (Gene_ID) P97454 (T2-S465) (Accession)
Molecular Weight
Approximately 57 kDa, based on SDS-PAGE under reducing conditions.
References & Citations
[1]Liu B, et al. Smad5: signaling roles in hematopoiesis and osteogenesis. Int J Biochem Cell Biol. 2004 May;36 (5) :766-70.|[2]Umans L, et al. Generation of a floxed allele of Smad5 for cre-mediated conditional knockout in the mouse. Genesis. 2003 Sep;37 (1) :5-11.
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
Scientific Category
Recombinant Proteins

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