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(+) -Penbutolol

CAT: 0804-HY-116790A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-116790A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(+) -Penbutolol is a β-adrenoceptor antagonist, with an IC50 of 0.74 μM[1]. (+) -Penbutolol is an optical isomer of l-penbutolol with Na+ channel-blocking action[2].
CAS Number
38363-41-6
Product Name Alternative
(R) -Penbutolol; (+) -Isopenbutolol
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/__addition__-Penbutolol.html
Purity
95.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@@H](COC1=C(C=CC=C1)C2CCCC2)CNC(C)(C)C
Molecular Formula
C18H29NO2
Molecular Weight
291.43
References & Citations
[1]Chen M, et al. Effects of beta-adrenoceptor antagonists on Ca (2+) -overload induced by lysophosphatidylcholine in rat isolated cardiomyocytes. Br J Pharmacol. 1996 Jun;118 (4) :865-70.|[2]Hashizume H, et al. Effects of antiischemic drugs on veratridine-induced hypercontracture in rat cardiac myocytes. Eur J Pharmacol. 1994 Dec 12;271 (1) :1-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
β adrenergic receptor

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