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TLR8 antibody

CAT: 0710-FNab10155Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10155Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
Synonyms
Toll-like receptor 8|TLR8
Gene ID
51311
UniProt
Q9NR97
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Toll-like receptor 8
Target
TLR8
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
120 kDa, 55 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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