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PRKCQ antibody

CAT: 0710-FNab10092Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10092Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.
Synonyms
Protein kinase C theta type|nPKC-theta|PRKCQ|PRKCT
Gene ID
5588
UniProt
Q04759
Host
Rabbit
Reactivity
Human
Immunogen
PRKCQ
Target
PRKCQ
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Cell Division and Proliferation, Signal Transduction, Metabolism, cancer, Immunology
Purification
Immunogen affinity purified
Dilution
IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
85 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC

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