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CD206 antibody

CAT: 0710-FNab09912Size: 100 µgDry Ice: NoHazardous: No
CAT#: FNab09912Size: 100 µg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane protein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. It is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia.
Synonyms
Macrophage mannose receptor 1 (MMR) |C-type lectin domain family 13 member D|C-type lectin domain family 13 member D-like|Human mannose receptor (hMR) |Macrophage mannose receptor 1-like protein 1|MRC1|CLEC13D|CLEC13DL|MRC1L1
Gene ID
4360
UniProt
P22897
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Mannose receptor, C type 1
Target
CD206
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Neuroscience, Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
166 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
19-148aa

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