ITGAE antibody

• Background:

  Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.

• Synonyms:

  Integrin alpha-E|HML-1 antigen|Integrin alpha-IEL|Mucosal lymphocyte 1 antigen|Integrin alpha-E light chain|Integrin alpha-E heavy chain|ITGAE

• Gene ID:

  3682

• UniProt:

  P38570

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  ITGAE

• Target:

  ITGAE

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  110 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB