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KDR antibody

CAT: 0710-FNab09795Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09795Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas.
Synonyms
Vascular endothelial growth factor receptor 2 (VEGFR-2) |Fetal liver kinase 1 (FLK-1) |Kinase insert domain receptor (KDR) |Protein-tyrosine kinase receptor flk-1|KDR|FLK1|VEGFR2
Gene ID
3791
UniProt
P35968
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Vascular endothelial growth factor receptor 2
Target
KDR
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB,FC
Field of Research
Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
200 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB, FC

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