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WDR24 antibody

CAT: 0710-FNab09488Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09488Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway (PubMed:23723238, PubMed:27166823) . Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway (PubMed:23723238) . Functions downstream of and is regulated by amino acid sensors like SESN2 (PubMed:26449471, PubMed:26586190) . In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux (PubMed:27166823) .
Synonyms
GATOR2 complex protein WDR24|WD repeat-containing protein 24|WDR24|C16orf21
Gene ID
84219
UniProt
Q96S15
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
WD repeat domain 24
Target
WDR24
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Cell Division and Proliferation
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000; IP: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
102 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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