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WDR1 antibody

CAT: 0710-FNab09481Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09481Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins (PubMed:15629458) . Enhances cofilin-mediated actin severing (By similarity) . Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions (PubMed:18494608) . Involved in myocardium sarcomere organization. Required for cardiomyocyte growth and maintenance (By similarity) . Involved in megakaryocyte maturation and platelet shedding. Required for the establishment of planar cell polarity (PCP) during follicular epithelium development and for cell shape changes during PCP; the function seems to implicate cooperation with CFL1 and/or DSTN/ADF. Involved in the generation/maintenance of cortical tension (By similarity) . Involved in assembly and maintenance of epithelial apical cell junctions and plays a role in the organization of the perijunctional actomyosin belt (PubMed:25792565) .
Synonyms
WD repeat-containing protein 1|Actin-interacting protein 1 (AIP1) |NORI-1|WDR1
Gene ID
9948
UniProt
O75083
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
WD repeat domain 1
Target
WDR1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, IP, WB
Field of Research
Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
66 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, IP, WB

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