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WAPL antibody

CAT: 0710-FNab09467Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09467Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The wings apart-like (WAPL, or WAPAL) protein was originally identified as a gene product that potentially regulates heterochromatin organization in Drosophila melanogaster. Human WAPL is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase. Overexpression of WAPL disturbs mitosis and cytokinesis, and contributes to tumor progression by induction of chromosomal instability.
Synonyms
Wings apart-like protein homolog|Friend of EBNA2 protein|WAPL cohesin release factor|WAPL|FOE|KIAA0261|WAPAL
UniProt
Q7Z5K2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Wings apart-like homolog (Drosophila)
Target
WAPL
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Epigenetics
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
140 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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