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VAMP7 antibody

CAT: 0710-FNab09364Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09364Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
VAMP7, also named as SYBL1 and TI-VAMP, belongs to the synaptobrevin family. It is involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. VAMP7 is required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. It is required for calcium regulated lysosomal exocytosis. VAMP7 is involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. It is required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. It is also required for focal exocytosis of late endocytic vesicles during phagosome formation. The antibody is specific to VAMP7.
Synonyms
Vesicle-associated membrane protein 7 (VAMP-7) |Synaptobrevin-like protein 1|Tetanus-insensitive VAMP (Ti-VAMP) |VAMP7|SYBL1
UniProt
P51809
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Vesicle-associated membrane protein 7
Target
VAMP7
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100; IP: 1:500-1:5000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
20 kDa, 50 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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