UCHL5 antibody

• Background :

  Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.

• Synonyms :

  Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) |Ubiquitin C-terminal hydrolase UCH37|Ubiquitin thioesterase L5|UCHL5|UCH37

• Gene ID :

  51377

• UniProt :

  Q9Y5K5

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Ubiquitin carboxyl-terminal hydrolase L5

• Target :

  UCHL5

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, IHC, WB

• Field of Research :

  Epigenetics, Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:200-1:1000; IHC:1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  37 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, IHC, WB