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UCHL1 antibody

CAT: 0710-FNab09218Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09218Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
UCHL1 (Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons (PMID: 6343558) . This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm (PMID:7217993) . And UCHL1 is a Parkinson's disease susceptibility gene (PMID:15048890) .
Synonyms
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1) |Neuron cytoplasmic protein 9.5|PGP 9.5 (PGP9.5) |Ubiquitin thioesterase L1|UCHL1
Gene ID
7345
UniProt
P09936
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
Target
UCHL1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Neuroscience, Cancer, Metabolism, Epigenetics
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000; IHC:1:100-1:500; IP: 1:1000-1:5000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
26 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP
Immunogen Sequence
1-220aa

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