UBE2A antibody

• Background :

  The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants.

• Synonyms :

  Ubiquitin-conjugating enzyme E2 A|E2 ubiquitin-conjugating enzyme A|RAD6 homolog A (HR6A, hHR6A) |Ubiquitin carrier protein A|Ubiquitin-protein ligase A|UBE2A|RAD6A

• Gene ID :

  7319

• UniProt :

  P49459

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Ubiquitin-conjugating enzyme E2A (RAD6 homolog)

• Target :

  UBE2A

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC

• Field of Research :

  Epigenetics, Cell Division and Proliferation, Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  17 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC